The second-place Chicago Cubs (60-46) continue their road trip tonight at Busch Stadium as they take on the St. Louis Cardinals (53-53) in the second game of this NL Central series. Chicago enters play six games behind Milwaukee in the division race and looking to build momentum after a win last night, while St. Louis is trying to halt a slide over the last two weeks that has seen them drop eight of their last ten games and fall back to .500.
The Cubs opened the series with a 7-3 victory over the Cardinals on last night. Chicago’s offense erupted for 14 hits, led by Alex Bregman, who broke out of an 0-for-12 slump by going 4-for-5 with a homer, two doubles, two RBIs, and three runs scored. Nico Hoerner also collected four hits, including a two-run homer in the ninth inning that put the game away. The Cubs received a solid outing from recently acquired left-hander David Peterson, who worked 5⅔ innings and allowed two runs. For St. Louis, José Fermín homered and Masyn Winn and Bryan Torres drove in runs, but the Cards were unable to overcome an early deficit created by Chicago’s relentless offense.
The veteran Colin Rea (7-7, 4.85 ERA) gets the ball for Chicago looking to provide stability behind a Cubs’ offense that has scored 25 runs over their last 3 games. Rea’s most recent start came on July 22 against Detroit, when he took the loss after allowing four runs on six hits over five innings, striking out five while surrendering a pair of home runs. Prior to that outing, Rea delivered a quality six-inning effort against Minnesota, allowing three earned runs while striking out six.
Michael McGreevy (4-8, 3.07 ERA) takes the mound for the Cardinals. The right-hander enters with a strong 1.13 WHIP, among the best marks on the Cardinals’ staff. His most recent start came July 23 against Arizona, when he suffered a 10-6 loss despite pitching into the seventh inning. McGreevy allowed four runs on seven hits over 6⅓ innings, walking three and striking out three. Before that setback, he was excellent against the Diamondbacks and Brewers, posting back-to-back victories while allowing just two earned runs combined over 12⅔ innings.
Lets dive into tonight’s game and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game Details and How to Watch: Cubs vs. Cardinals
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Date: Tuesday, July 28, 2026
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Network/Streaming: MLB.TV, Marquee Sports Network, YBS, Cardinals.TV
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The Latest Odds: Cubs vs. Cardinals
The latest odds as of Tuesday courtesy of DraftKings:
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Moneyline: Chicago Cubs (-114), St. Louis Cardinals (-105)
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Spread: Cubs -1.5 (+144), Cardinals +1.5 (-175)
Probable Starting Pitchers and their Stats: Cubs vs. Cardinals for July 28
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Cubs: Colin Rea
Season Totals: 105.2 IP, 7-7, 4.85 ERA, 1.42 WHIP, 81K, 38 BB -
Cardinals: Michael McGreevey
Season Totals: 114.1 IP, 4-8, 3.07 ERA, 1.13 WHIP, 74K, 27 BB
Who’s Hot? Who’s Not! Cubs vs. Cardinals
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Nico Hoerner has hit safely in 4 straight (8-17) and 8 of his last 9 games (19-40)
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Alex Bregman collected 4 hits last night to snap a 0-12 streak
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Pete Crow-Armstrong was 0-3 last night to snap a 3-game stretch in which he collected 7 hits in 14 ABs
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Michael Busch is 3-8 with 2 HRs in his career against Michael McGreevey
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Jordan Walker is 0-7 over his last 2 games and just 2-15 over his last 4
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Ivan Herrera is riding a modest 3-game hitting streak (5-13)
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Top Betting Trends & Insights: Cubs vs. Cardinals
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The Cubs are 48-58 on the Run Line this season
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The Cardinals are 58-48 on the Run Line this season
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The OVER has cashed an MLB-worst 42 times in St. Louis’ 106 games this season (42-58-6)
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The OVER has cashed 57 times in Chicago’s 106 games this season (57-48-1)
Expert picks & predictions: Cubs vs. Cardinals
Rotoworld Bet Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model for tonight’s game between the Cubs and the Cardinals:
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Moneyline: Rotoworld Bet is leaning towards a play on the Cubs on the Moneyline.
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Spread: Rotoworld Bet is staying away from a play on the Run Line.
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Total: Rotoworld Bet is recommending a play on the Game Total OVER 9.0.
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