Twins at Orioles prediction: Odds, expert picks, starting pitchers, betting trends, and stats for May 15

Its Thursday, May 15 and the Twins (2-320) are in Baltimore to take on the Orioles (15-26).

Chris Paddack is slated to take the mound for Minnesota against Tomoyuki Sugano for Baltimore.

The Twins have now won 10 straight following a pair of wins over the Orioles yesterday. Christian Vazquez and Brooks Lee went deep in the opener to lead the Twins to a 6-3 win. Minnesota rallied for three in the eighth on Kody Clemens’ home run to cap a comeback and complete the sweep with an 8-6 win.

Lets dive into this afternoon’s matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Twins at Orioles

• Date: Thursday, May 15, 2025
• Time: 12:35PM EST
• Site: Oriole Park at Camden Yards
• City: Baltimore, MD
• Network/Streaming: MNNT, MASN2, MLBN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Twins at the Orioles

The latest odds as of Thursday:

• Moneyline: Twins (+114), Orioles (-134)
• Spread: Orioles -1.5
• Total: 9.0 runs

Probable starting pitchers for Twins at Orioles

• Pitching matchup for May 15, 2025: Chris Paddack vs. Tomoyuki Sugano
  • Twins: Chris Paddack (1-3, 4.77 ERA)
    Last outing: 5/9 vs. San Francisco – 7.1IP, 1ER, 3H, 0BB, 6Ks
  • Orioles: Tomoyuki Sugano (4-2, 2.72 ERA)
    Last outing: 5/9 at Angels – 7.1IP, 1ER, 3H, 0BB, 5Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Twins at Orioles

• The Twins are on an 10-game winning streak
• The Twins have covered the Run Line in 9 of the last 10 games
• Carlos Correa is 12-40 in May (.300)
• Adley Rutschman is just 5-38 in May (.132)

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for today’s game between the Twins and the Orioles

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Thursday’s game between the Twins and the Orioles:

• Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Minnesota Twins at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 9.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
• Drew Dinsick (@whale_capper)
• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)