Royals at White Sox prediction: Odds, expert picks, starting pitchers, betting trends, and stats for June 6

Its Friday, June 6 and the Royals (33-30) are in Chicago to take on the White Sox (20-43).

Seth Lugo is slated to take the mound for Kansas City against Davis Martin for Chicago.

The White Sox welcome the Royals into town following a split of a four-game series against the AL Central-leading Tigers. Tim Elko drove in the game-winner in the tenth inning in a 3-2 win for the ChiSox yesterday. The Royals come to town having taken two of three from the Cardinals in St. Louis. Maikel Garcia went 2-3 and drove in a pair of runs to pace the attack for KC in a 7-5 win last night.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Royals at White Sox

• Date: Friday, June 6, 2025
• Time: 7:40PM EST
• Site: Rate Field
• City: Chicago, IL
• Network/Streaming: FDSNKC, CHSN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Royals at the White Sox

The latest odds as of Friday:

• Moneyline: Royals (-176), White Sox (+147)
• Spread: Royals -1.5
• Total: 8.0 runs

Probable starting pitchers for Royals at White Sox

• Pitching matchup for June 6, 2025: Seth Lugo vs. Davis Martin
  • Royals: Seth Lugo (3-5, 3.45 ERA)
    Last outing: 5/30 vs. Detroit – 3.1IP, 4ER, 5H, 2BB, 3Ks
  • White Sox: Davis Martin (2-6, 3.67 ERA)
    Last outing: 5/31 at Baltimore – 6IP, 4ER, 5H, 1BB, 3Ks

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Top betting trends & insights to know ahead of Royals at White Sox

• The Royals have won 4 of their last 5 road games against teams with losing records
• The Over is 4-1 in the White Sox’s last 5 games against AL Central teams
• The White Sox are showing a profit of 2.39 units on the Run Line in their last 5 games at Rate Field
• Bobby Witt Jr. has at least one hit in four straight games (5-16)
• Seth Lugo has averaged 4 Ks per start over his last 4 starts

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Royals and the White Sox

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Friday’s game between the Royals and the White Sox:

• Moneyline: NBC Sports Bet is recommending a play on the Kansas City Royals on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

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• Jay Croucher (@croucherJD)
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• Brad Thomas (@MrBradThomas)