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Home»Baseball»Reds at Nationals Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for July 21
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Reds at Nationals Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for July 21

News RoomBy News RoomJuly 21, 2025No Comments4 Mins Read
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Reds at Nationals Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for July 21

Its Monday, July 21 and the Reds (52-48) are in Washington to take on the Nationals (39-60). Brady Singer is slated to take the mound for Cincinnati against Jake Irvin for Washington.

The Reds narrowly swept the Mets to start the second-half but dropped Sunday’s outing, 3-2. The Nationals lost its series to the Padres, dropping two out of three games and being outscored 17-7.

This is the second meeting of the season between the two teams. Washington won the first series, 2-1, losing the first game then winning the next two. The Nationals outscored the Reds, 16-13 over the three games.

Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Reds at Nationals

  • Date: Monday, July 21, 2025
  • Time: 6:45PM EST
  • Site: Nationals Park
  • City: Washington, DC
  • Network/Streaming: FDSNOH, MASN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Reds at the Nationals

The latest odds as of Monday:

  • Moneyline: Reds (-135), Nationals (+114)
  • Spread: Reds -1.5
  • Total: 9.0 runs

Probable starting pitchers for Reds at Nationals

  • Pitching matchup for July 21, 2025: Brady Singer vs. Jake Irvin
    • Reds: Brady Singer, (7-7, 4.32 ERA)
      Last outing: 6.1 Innings Pitched, 3 Earned Runs Allowed, 7 Hits Allowed, 1 Walk, and 9 Strikeouts
    • Nationals: Jake Irvin, (7-5, 4.58 ERA)
      Last outing: 5.0 Innings Pitched, 0 Earned Runs Allowed, 4 Hits Allowed, 1 Walk, and 5 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Expert picks & predictions for tonight’s game between the Reds and the Nationals

Rotoworld Best Bet

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Monday’s game between the Reds and the Nationals:

  • Moneyline: NBC Sports Bet is recommending a play on the Cincinnati Reds on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Washington Nationals at +1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 9.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.

Top betting trends & insights to know ahead of Reds at Nationals

  • Washington is 10-10 when Irvin pitches this season
  • Cincinnati is 10-8 when Singer pitches this season
  • The Reds have won 4 of their last 5 matchups against NL East teams
  • The Over is 4-1 in the Nationals’ last 5 matchups against National League teams

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Trysta Krick (@Trysta_Krick)



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