Preparing to defend their World Series crown, the Dodgers seemed to awaken from their summer slumber in the final week or two of the regular season winning nine of their last 11 games. They carried that momentum into Game 1 of their Wild Card series last night at Chavez Ravine, jumping out to an 8-0 lead before ultimately winning 10-5. Shohei Ohtani led off the bottom of the first with a home run. He and Teoscar Hernandez each homered twice in the win and Blake Snell was dominant allowing two runs on four hits over seven innings while striking out nine.
LA’s bullpen was leaky and that should make Dodger Nation a bit nervous, but seeing Snell control the game and the bats come alive is without question a combination the rest of baseball noticed.
Game 2 is now a must-win for Cincinnati. They will send Zach Littell to the mound while the Dodgers will counter with Yoshinobu Yamamoto. Yamamoto made 30 starts this season finishing with 12 wins and the fourth-best ERA in baseball at 2.49. Littell carries a regular season record of 10-8 with a 3.81 ERA into the contest. Cincinnati has won his last four starts.
Lets take a closer look at the number for Game 2 and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Reds at Dodgers – Game 2
- Date: Wednesday, October 1, 2025
- Time: 9:08PM EST
- Site: Dodger Stadium
- City: Los Angeles, CA
- Network/Streaming: ESPN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Reds at the Dodgers – Game 2
The latest odds as of Wednesday courtesy of DraftKings:
- Moneyline: Cincinnati Reds (+223), LA Dodgers (-281)
- Spread: Dodgers -1.5 (-132)
- Total: 8.0 runs
Probable starting pitchers for Reds at Dodgers – Game 2
- Pitching matchup for October 1, 2025: Zack Littell vs. Yoshinobu Yamamoto
- Reds: Zack Littell (10-8, 3.81)
Acquired from Tampa Bay at the deadline, Littell closed the season strong allowing 3 runs over his final 2 starts (9.2 IP) - Dodgers: Yoshinobu Yamamoto (12-8, 2.49 ERA)
Yamamoto has not allowed a run over his last 2 starts (11.1 IP) and just 3 runs over his last 5 starts (34 IP)
- Reds: Zack Littell (10-8, 3.81)
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Top betting trends & insights to know ahead of Reds at Dodgers
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s Game 2 between the Reds and the Dodgers
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Wednesday’s game between the Reds and the Dodgers:
- Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Los Angeles Dodgers at -1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
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