Its Wednesday, May 21 and the Mariners (27-20) are in Chicago to take on the White Sox (15-34).
Logan Evans is slated to take the mound for Seattle against Shane Smith for Chicago.
The series is not tied at one game apiece. Adrian Houser combined with four relievers to shutout the Mariners last night, 1-0. Seattle managed just four hits off the Sox hurlers.
Lets dive into the matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Mariners at White Sox
- Date: Wednesday, May 21, 2025
- Time: 2:10PM EST
- Site: Rate Field
- City: Chicago, IL
- Network/Streaming: RSNW, CHSN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Mariners at the White Sox
The latest odds as of Wednesday:
- Moneyline: Mariners (-151), White Sox (+127)
- Spread: Mariners -1.5
- Total: 8.0 runs
Probable starting pitchers for Mariners at White Sox
- Pitching matchup for May 21, 2025: Logan Evans vs. Shane Smith
- Mariners: Logan Evans (2-1, 2.57 ERA)
Last outing: 5/16 at San Diego – 6IP, 0ER, 7H, 1BB, 3Ks - White Sox: Shane Smith (1-3, 2.05 ERA)
Last outing: 5/16 at Cubs – 5IP, 1ER, 7H, 1BB, 5Ks
- Mariners: Logan Evans (2-1, 2.57 ERA)
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Top betting trends & insights to know ahead of Mariners at White Sox
- The Mariners are 4-1 in their last 5 games
- The Mariners’ last 5 road games have stayed under the Total
- The Mariners have covered in 4 of their last 5 games for a profit of 2.04 units
- Cal Raleigh is 1-12 (.083) over his last 3 games
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for today’s game between the Mariners and the White Sox
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Wednesday’s game between the Mariners and the White Sox:
- Moneyline: NBC Sports Bet is recommending a play on the Seattle Mariners on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
- Drew Dinsick (@whale_capper)
- Vaughn Dalzell (@VmoneySports)
- Brad Thomas (@MrBradThomas)
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