Guardians at Astros prediction: Odds, expert picks, starting pitchers, betting trends, and stats for July 9

Its Wednesday, July 9 and the Guardians (42-48) are in Houston to take on the Astros (55-37).

Slade Cecconi is slated to take the mound for Cleveland against Brandon Walter for Houston.

Walter and the Astros will be looking to avoid the sweep as Cleveland has taken the first two games of the series. Last night, Houston rallied from a 6-1 deficit after just four innings but lost in ten innings, 10-6. All-Star Hunter Brown was bad early (6ER in 6IP) and fellow All-Star Josh Hader was bad late (3ER in 1.2IP). Angel Martinez’ grand slam in the tenth was the difference in the game.

Lets dive into tonight’s matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Guardians at Astros

• Date: Wednesday, July 9, 2025
• Time: 8:10PM EST
• Site: Minute Maid Park
• City: Houston, TX
• Network/Streaming: CLEG, SCHN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Guardians at the Astros

The latest odds as of Wednesday:

• Moneyline: Guardians (+119), Astros (-142)
• Spread: Astros -1.5
• Total: 8.0 runs

Probable starting pitchers for Guardians at Astros

• Pitching matchup for July 9, 2025: Slade Cecconi vs. Brandon Walter
  • Guardians: Slade Cecconi (3-4, 3.56 ERA)
    Last outing: 7/4 vs. Detroit – 6IP, 2ER, 6H, 2BB, 5Ks
  • Astros: Brandon Walter (1-1, 4.15 ERA)
    Last outing: 7/3 at Colorado – 5IP, 5ER, 8H, 0BB, 3Ks

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Top betting trends & insights to know ahead of Guardians at Astros

• The Guardians have won 2 straight after losing their previous 10 games
• 4 of the Guardians’ last 5 games in Houston have gone over the Total
• The Guardians have covered in their last 3 games against the Astros
• With 2 hits last night, Jose Altuve has 12 hits in his last 27ABs
• Jose Ramirez has hit safely in 4 of his last 5 games (6-18)

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Guardians and the Astros

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday’s game between the Guardians and the Astros:

• Moneyline: NBC Sports Bet is recommending a play on the Houston Astros on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Cleveland Guardians at +1.5.
• Total: NBC Sports Bet is leaning towards a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

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