Its Tuesday, July 8 and the Guardians (41-48) are in Houston to take on the Astros (55-36) in the second game of their three-game series.
Joey Cantillo is slated to take the mound for Cleveland against Hunter Brown for Houston.
The Guardians won the series opener last night, 7-5, to snap a ten-game losing streak. Jose Ramirez and David Fry each homered to spark the Guardians’ attack and Houston’s offense was limited to just five hits by Tanner Bibee and four relievers.
Lets dive into Game 2 and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Guardians at Astros
- Date: Tuesday, July 8, 2025
- Time: 8:10PM EST
- Site: Minute Maid Park
- City: Houston, TX
- Network/Streaming: CLEG, SCHN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Guardians at the Astros
The latest odds as of Tuesday:
- Moneyline: Guardians (+171), Astros (-207)
- Spread: Astros -1.5
- Total: 7.0 runs
Probable starting pitchers for Guardians at Astros
- Pitching matchup for July 8, 2025: Joey Cantillo vs. Hunter Brown
- Guardians: Joey Cantillo (1-0, 3.41 ERA)
Last outing: 7/3 at Cubs – 3.1IP, 0ER, 2H, 3BB, 5Ks - Astros: Hunter Brown (9-3, 1.82 ERA)
Last outing: 7/2 at Colorado – 6IP, 2ER, 6H, 1BB, 8Ks
- Guardians: Joey Cantillo (1-0, 3.41 ERA)
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Top betting trends & insights to know ahead of Guardians at Astros
- The Astros have won their last 7 games with Hunter Brown on the bump
- The Astros’ last 4 games have gone under the Total with Hunter Brown starting
- Betting the Astros on the Run Line with Hunter Brown as the starter has returned a 2.87-unit profit in 2025
- Isaac Paredes is enjoying a 6-game hitting streak (9-28)
- Christian Walker has hit in 6 straight (12-28) and 9 of his last 10 games (15-43) to raise his average on the season to .231
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s game between the Guardians and the Astros
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Tuesday’s game between the Guardians and the Astros:
- Moneyline: NBC Sports Bet is recommending a play on the Houston Astros on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Cleveland Guardians at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 7.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
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- Brad Thomas (@MrBradThomas)
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