Diamondbacks at Giants prediction: Odds, expert picks, starting pitchers, trends, and stats for May 14

Its Wednesday, May 14 and the Diamondbacks (22-20) are in San Francisco to take on the Giants (24-18).

Eduardo Rodriguez is slated to take the mound for Arizona against Jordan Hicks for San Francisco.

The Giants took Game 2 of this three-game series last night, 10-6. Christian Koss belted his first career home run…and it was a grand slam to help the Giants earn the win. Josh Naylor went 2-5 and drove in four runs for Arizona in the loss.

Lets dive into today’s matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Diamondbacks at Giants

• Date: Wednesday, May 14, 2025
• Time: 3:45PM EST
• Site: Oracle Park
• City: San Francisco, CA
• Network/Streaming: ARID, NBCSBA, MLBN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Diamondbacks at the Giants

The latest odds as of Wednesday:

• Moneyline: Diamondbacks (-110), Giants (-109)
• Spread: Diamondbacks -1.5
• Total: 8.0 runs

Probable starting pitchers for Diamondbacks at Giants

• Pitching matchup for May 14, 2025: Eduardo Rodriguez vs. Jordan Hicks
  • Diamondbacks: Eduardo Rodriguez (1-3, 6.86 ERA)
    Last outing: 5/9 vs. Dodgers – 2.2IP, 6ER, 9H, 3BB, 3Ks
  • Giants: Jordan Hicks (1-4, 5.82 ERA)
    Last outing: 5/9 at Minnesota – 6IP, 3ER, 7H, 0BB, 6Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Diamondbacks at Giants

• The Giants snapped a 4-game losing streak with the win last night
• The OVER is 25-18 this season in Giants’ games
• Corbin Carroll is 4-8 with 3 HRs in the first 2 games of this series

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for today’s game between the Diamondbacks and the Giants

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday’s game between the Diamondbacks and the Giants:

• Moneyline: NBC Sports Bet is recommending a play on the Arizona Diamondbacks on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the San Francisco Giants at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
• Drew Dinsick (@whale_capper)
• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)