Game 2 of the four-game series between the Cubs (1-2) and the Diamondbacks (0-1) is tonight in Arizona.

Jameson Taillon is slated to take the mound for Chicago against Merrill Kelly for Arizona

The opener yesterday was a runfest with the Cubs outlasting the Diamondbacks, 10-6. Chicago backstop Miguel Amaya collected a couple hits and five RBIs to pace the attack for Chicago which collected 12 hits.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Cubs at Diamondbacks

  • Date: Friday, March 28, 2025
  • Time: 9:40PM EST
  • Site: Chase Field
  • City: Phoenix, AZ
  • Network/Streaming: MSN, DBacks.TV

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Cubs at the Diamondbacks

The latest odds as of Friday:

  • Moneyline: Cubs (+112), Diamondbacks (-133)
  • Spread: Diamondbacks -1.5
  • Total: 8.0 runs

Probable starting pitchers for Cubs at Diamondbacks

  • Friday’s pitching matchup March 28, 2025: Jameson Taillon vs. Merrill Kelly
    • Cubs: Jameson Taillon
      2024 – 28GP, 165.1 IP, 12-8, 3.27 ERA, 125 Ks
    • Diamondbacks: Merrill Kelly
      2024 – 13GP, 73.2 IP, 5-1, 4.03 ERA, 63 Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Cubs at Diamondbacks

  • Justin Steele allowed 3 runs in 5 innings to pick up the win for the Cubs last night.
  • Kyle Tucker is now 2-13 on the season after going 1-5 yesterday for the Cubs
  • Ketel Marte collected a couple hits and scored a couple runs in Game 1 of the series for Arizona
  • Usually a reliable hurler at home, Zac Gallen allowed 4 earned runs in just 4 innings last night

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Cubs and the Diamondbacks

NBC Sports Bet Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Friday’s game between the Cubs and the Diamondbacks:

  • Moneyline: NBC Sports Bet is recommending a play on the Arizona Diamondbacks on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Diamondbacks -1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Brad Thomas (@MrBradThomas)



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