Cubs at Blue Jays prediction: Odds, expert picks, starting pitchers, betting trends, and stats for August 13

Its Wednesday, August 13 and the Cubs (67-51) are in Toronto to take on the Blue Jays (70-50) in Game 2 of their three-game series.

Cade Horton is slated to take the mound for Chicago against Kevin Gausman for Toronto.

The Jays continued their dominant play at home last night opening the series with a 5-1 win. Ernie Clement went yard with two ducks on the pond in the fourth inning to break open the game. Jose Berrios allowed two hits over 5.1 innings to improve to 9-4 on the season.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Cubs at Blue Jays

• Date: Wednesday, August 13, 2025
• Time: 7:07PM EST
• Site: Rogers Centre
• City: Toronto, ON
• Network/Streaming: MARQ, Sportsnet

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Cubs at the Blue Jays

The latest odds as of Wednesday:

• Moneyline: Cubs (+109), Blue Jays (-129)
• Spread: Blue Jays -1.5
• Total: 8.0 runs

Probable starting pitchers for Cubs at Blue Jays

• Pitching matchup for August 13, 2025: Cade Horton vs. Kevin Gausman
  • Cubs: Cade Horton (6-3, 3.18 ERA)
    Last outing: August 6 vs. Cincinnati – 0.00 ERA, 0 Earned Runs Allowed, 2 Hits Allowed, 0 Walks, and 6 Strikeouts
  • Blue Jays: Kevin Gausman (8-8, 3.85 ERA)
    Last outing: August 6 at Colorado – 1.29 ERA, 1 Earned Runs Allowed, 3 Hits Allowed, 2 Walks, and 8 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Cubs at Blue Jays

• After losing the series opener on the road, the Cubs have a 10-3 record in Game 2 this season
• This season Kevin Gausman has an ERA of 3.86
• With Kevin Gausman starting the Blue Jays are up 0.75 units on the Run Line at Rogers Centre in 2025
• The Pete Crow-Armstrong MVP chatter has gone silent as the outfielder has started August with just 3 hits (2 singles and 1 double) in 37 ABs (.081)
• Vladimir Guererro Jr. is 15-43 (.349) in August

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Cubs and the Blue Jays

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday’s game between the Cubs and the Blue Jays:

• Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago Cubs at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
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• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)