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Home»Baseball»Cardinals at Reds Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for August 29
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Cardinals at Reds Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for August 29

News RoomBy News RoomAugust 31, 2025No Comments4 Mins Read
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Cardinals at Reds Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for August 29

It’s Friday, August 29 and the Cardinals (66-69) are in Cincinnati to take on the Reds (68-66). Matthew Liberatore is slated to take the mound for St. Louis against Zack Littell for Cincinnati.

The Cardinals are Reds are tied for the season series at four games apiece as they prepare for this three-game series. Both enter on bit of losing skids with St. Louis at 2-4 over the last six games and Cincinnati at 1-6 over the past seven (0-3 in the last three). The Reds are 4.0 games back of the final NL Wild Card spot while the Cardinals are 6.5 back.

Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Cardinals at Reds

  • Date: Friday, August 29, 2025
  • Time: 6:40PM EST
  • Site: Great American Ball Park
  • City: Cincinnati, OH
  • Network/Streaming: FDSNMW, FDSNOH

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Cardinals at the Reds

The latest odds as of Friday:

  • Moneyline: Cardinals (+106), Reds (-126)
  • Spread: Reds -1.5
  • Total: 9.0 runs

Probable starting pitchers for Cardinals at Reds

  • Pitching matchup for August 29, 2025: Matthew Liberatore vs. Zack Littell
    • Cardinals: Matthew Liberatore, (6-11, 4.27 ERA)
      Last outing: 8.31 ERA, 4 Earned Runs Allowed, 3 Hits Allowed, 3 Walks, and 5 Strikeouts
    • Reds: Zack Littell, (9-8, 3.58 ERA)
      Last outing: 9.00 ERA, 3 Earned Runs Allowed, 4 Hits Allowed, 3 Walks, and 3 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Cardinals at Reds

  • The two are tied at 4-4 on the season
  • Cincinnati is 0-3 in the last 3 games and 1-6 in the past 7
  • St. Louis is 2-4 in the last 6 games
  • The Over is 7-2-1 for the Cardinals’ and the Reds’ last 5 games combined
  • The Cardinals have failed to cover the Run Line in 5 of their last 6 games
  • The Cardinals have lost their last 3 games against teams with better records

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Cardinals and the Reds

Rotoworld Best Bet

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Friday’s game between the Cardinals and the Reds:

  • Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the St. Louis Cardinals at +1.5.
  • Total: NBC Sports Bet is leaning towards a play on the over on the Game Total of 9.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Trysta Krick (@Trysta_Krick)



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