San Diego (60-56) and Houston (59-57) prepare for a three-game weekend series that will conclude on Peacock Sunday. Both the Padres and Astros are two of the hottest teams in the second half of the season and the past two weeks.
After starting the second half of the year 0-3, Houston went on a 12-3 stretch. The Astros are hot and in the past 15 days, Houston has scored the fifth-most runs (65) and the third-best batting average (.284). To start August, the pitching staff has allowed a .186 OBA (4th) and the best WHIP (0.89). The Astros are 1.5 games up on the Rangers for the AL West lead and 3.0 ahead of the Mariners.
San Diego has now won four-straight games following a loss as the Padres continue to stay hot. The Padres are 10-3 in the past 13 games. The pitching staff has a 3.60 ERA in that 13-game span, and the 2nd-best batting average at .286
Fernando Tatis’ bat has been hot the last 6-8 weeks, while Manny Machado is coming off his best month in July with 7 home runs and 19 RBI on a .292 batting average. San Diego is 1.0 game back of the Diamondbacks for the final Wild Card spot and 2.0 of the Phillies entering this series.
Let’s dive into tonight’s matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Astros at Padres
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Date: Friday, August 7, 2026
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Network/Streaming: MLB TV
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Odds for the Astros at the Padres
The latest odds as of Friday:
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Spread: Astros +1.5 (-193), Padres -1.5 (+159)
Probable starting pitchers for Astros at Padres
2026 stats: 122.2 IP, 10-6, 3.08 ERA, 1.29 WHIP, 107 K, 57 BB
2026 Stats: 14.2 IP, 0-1, 7.36 ERA, 1.30 WHIP, 16 K, 8 BB
Who’s Hot? Who’s Not
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Fernando Tatis Jr is hitting .150 in August (3/20)
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Manny Machado hit .292 in July with seven home runs on 28 hits
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Jose Altuve is hitting .450 in August (9/20) with zero strikeouts
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Top betting trends & insights to know ahead of Astros at Padres
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San Diego is 63-53 ATS, ranking fourth-best
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Arizona is 62-54 ATS, ranking tied for eighth-best
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San Diego is 62-53-1 to the Under, ranking 10th-best
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Arizona is 61-49-6 to the Under, ranking fifth-best
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San Diego is 30-27 ATS at home
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Arizona is 31-28 ATS on the road
Expert picks & predictions for tonight’s game between the Padres and the Astros
Rotoworld Bet Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Friday’s game between the Padres and the Astros:
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Moneyline: NBC Sports Bet is recommending a play on the Padres on the Moneyline.
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Spread: NBC Sports Bet is leaning towards a play ATS on the Padres at -1.5.
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Total: NBC Sports Bet is recommending a play on the Under on the Game Total of 8.5
Follow our experts on socials to keep up with all the latest content from the staff:
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Jay Croucher (@croucherJD)
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Drew Dinsick (@whale_capper)
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Vaughn Dalzell (@VmoneySports)
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Trysta Krick (@Trysta_Krick)
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