It’s Friday, July 25 and the Cubs (60-42) are in Chicago to take on the White Sox (37-66). Shota Imanaga is slated to take the mound for Chicago against Adrian Houser for Chicago.
The Cubs are 1-3 in the past four games and coming off a series loss to the Royals where they dropped two of three.
On the other hand, White Sox are one of the hottest teams in the second half with a 5-1 record and series wins over Tampa Bay and Pittsburgh.
Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Cubs at White Sox
- Date: Friday, July 25, 2025
- Time: 7:40PM EST
- Site: Rate Field
- City: Chicago, IL
- Network/Streaming: MARQ, CHSN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Cubs at the White Sox
The latest odds as of Friday:
- Moneyline: Cubs (-187), White Sox (+154)
- Spread: Cubs -1.5
- Total: 8.0 runs
Probable starting pitchers for Cubs at White Sox
- Pitching matchup for July 25, 2025: Shota Imanaga vs. Adrian Houser
- Cubs: Shota Imanaga, (7-3, 2.40 ERA)
Last outing: 0.00 ERA, 0 Earned Runs Allowed, 5 Hits Allowed, 1 Walks, and 5 Strikeouts - White Sox: Adrian Houser, (5-2, 1.89 ERA)
Last outing: 6.23 ERA, 3 Earned Runs Allowed, 10 Hits Allowed, 1 Walks, and 5 Strikeouts
- Cubs: Shota Imanaga, (7-3, 2.40 ERA)
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Expert picks & predictions for tonight’s game between the Cubs and the White Sox
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Friday’s game between the Cubs and the White Sox:
- Moneyline: NBC Sports Bet is recommending a play on the Chicago Cubs on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.
Top betting trends & insights to know ahead of Cubs at White Sox
- Chicago is 4-1 in Imanga’s last five starts
- The Cubs are on a 4-game win streak at the White Sox
- The Under is 7-3 in the Cubs’ last 10 road games
- The Cubs have covered in their last 4 games against the White Sox
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
- Drew Dinsick (@whale_capper)
- Vaughn Dalzell (@VmoneySports)
- Trysta Krick (@Trysta_Krick)
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