It’s Thursday, May 22 and the Brewers (24-26) are in Pittsburgh to take on the Pirates (17-33). Milwaukee has not announced its starter yet, while Mike Burrows makes his 2025 debut for Pittsburgh.
The Pirates snapped a four-game losing streak with back-to-back wins over the Reds in the last two days. Pittsburgh is 5-14 in May so far, while Milwaukee is 8-11 with three of those wins coming over the past four games.
Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Brewers at Pirates
- Date: Thursday, May 22, 2025
- Time: 6:40 PM EST
- Site: PNC Park
- City: Pittsburgh, PA
- Network/Streaming: FDSNWI, SNP
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Odds for the Brewers at the Pirates
The latest odds as of Thursday:
- Moneyline: Brewers (-120), Pirates (+102)
- Spread: Brewers -1.5
- Total: 9.0 runs
Probable starting pitchers for Brewers at Pirates
- Pitching matchup for May 22, 2025:
- TBD vs. Mike Burrows
- Brewers: TBD
- Pirates: Mike Burrows, (1-0, 2.70 ERA in 2024)
Last outing: This will be his first start in 2025
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Expert picks & predictions for tonight’s game between the Brewers and the Pirates
Rotoworld Best Bet Vaughn Dalzell (@VmoneySports) likes the value on Oneil Cruz to steal a base at +290:
“As someone holding a 150-to-1 ticket on Oneil Cruz to lead the MLB in stolen bases, it’s an everyday commitment to pay attention to this Pirates offense. Pittsburgh is on a historically bad run right now with four or fewer runs scored in 26 straight games! However, they did score three runs yesterday and were aggressive — which is usually what they aspire to be in division games.
At +290 to +350, I think Cruz to steal a base is a good bet against divisional opponents. Cruz to steal two-plus bases at +3000 or better will be a sprinkle each game (he did it on Tuesday).”
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Thursday’s game between the Brewers and the Pirates:
- Moneyline: NBC Sports Bet is recommending a play on the Milwaukee Brewers on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Pittsburgh Pirates at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 9.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
Top betting trends & insights to know ahead of Brewers at Pirates
- The Pirates have lost 12 of 16 games this season following a win
- The Under is 4-0-1 in the Pirates’ last 5 matchups against NL Central teams
- The Pirates are up 2.31 units on the Run Line in their last 5 games at PNC Park
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
- Drew Dinsick (@whale_capper)
- Vaughn Dalzell (@VmoneySports)
- Brad Thomas (@MrBradThomas)
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