Orioles at Twins Prediction: Odds, expert picks, starting pitchers, betting trends and stats for May 8

Its Thursday, May 8 and the Orioles (13-21) are in Minneapolis to take on the Twins (16-20).

Dean Kremer is slated to take the mound for Baltimore against Joe Ryan for Minnesota.

The Twins take the field looking for a sweep of the three-game series following their 5-2 win last night. Byron Buxton went yard for the third straight game and Harrison Bader also homered while six Minnesota hurlers allowed ten hits but combined to hold the O’s to two runs.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Orioles at Twins

• Date: Thursday, May 8, 2025
• Time: 1:10PM EST
• Site: Target Field
• City: Minneapolis, MN
• Network/Streaming: MASN, MNNT, MLBN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Orioles at the Twins

The latest odds as of Thursday:

• Moneyline: Orioles (+133), Twins (-158)
• Spread: Twins -1.5
• Total: 8.0 runs

Probable starting pitchers for Orioles at Twins

• Pitching matchup for May 8, 2025: Dean Kremer vs. Joe Ryan
  • Orioles: Dean Kremer (3-4, 5.74 ERA)
    Last outing: 5/2 vs. Kansas City – 7IP, 0ER, 3H, 1BB, 2Ks
  • Twins: Joe Ryan (2-2, 2.93 ERA)
    Last outing: 5/2 at Boston – 6IP, 1ER, 4H, 1BB, 8Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Orioles at Twins

• The Twins have won 4 in a row
• The Orioles have lost 4 in a row
• Gunnar Henderson has hit safely in 10 of his last 11 games (14-42)
• Adley Rutschman is 3-19 through 5 games in May
• Byron Buxton is riding a 7-game hitting streak (12-30)

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for today’s game between the Orioles and the Twins

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Thursday’s game between the Orioles and the Twins:

• Moneyline: NBC Sports Bet is recommending a play on the Minnesota Twins on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Baltimore Orioles at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
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• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)