Its Tuesday, April 22 and the Blue Jays (12-11) are in Houston to take on the Astros (11-11).
Chris Bassitt is slated to take the mound for Toronto against Ronel Blanco for Houston.
The Astros clawed their way back to a .500 record with a 7-0 win last night in the series opener. Hunter Brown’s early season case for the Cy Young remains strong as he threw seven shutout innings allowing just two hits while striking out nine Jays. The bottom three hitters in Houston’s lineup went a combined 5-10 with three RBIs to pace the attack.
Lets dive into the matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Blue Jays at Astros
- Date: Tuesday, April 22, 2025
- Time: 8:10PM EST
- Site: Minute Maid Park
- City: Houston, TX
- Network/Streaming: SN1, SCHN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Blue Jays at the Astros
The latest odds as of Tuesday:
- Moneyline: Blue Jays (-105), Astros (-114)
- Spread: Astros 1.5
- Total: 8.0 runs
Probable starting pitchers for Blue Jays at Astros
- Pitching matchup for April 22, 2025: Chris Bassitt vs. Ronel Blanco
- Blue Jays: Chris Bassitt (2-0, 0.77 ERA)
Last outing: 4/16 vs. Atlanta – 5IP, 0ER, 3H, 2BB, 10Ks - Astros: Ronel Blanco (1-2, 6.48 ERA)
Last outing: 4/16 at St. Louis – 5IP, 3ER, 5H, 3BB, 1K
- Blue Jays: Chris Bassitt (2-0, 0.77 ERA)
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Top betting trends & insights to know ahead of Blue Jays at Astros
- Isaac Paredes is 3-24 (.125) over his last 7 games
- Vlad Guerrero Jr. is 6-17 (.353) over his last 5 games
- The Under has cashed in the Astros’ last 3 games
- The Blue Jays have covered in 4 of their last 5 road games and are profiting 1.12 units
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s game between the Blue Jays and the Astros
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Tuesday’s game between the Blue Jays and the Astros:
- Moneyline: NBC Sports Bet is recommending a play on the Houston Astros on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Toronto Blue Jays at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
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- Vaughn Dalzell (@VmoneySports)
- Brad Thomas (@MrBradThomas)
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