The Arizona Diamondbacks (41-39) made it two straight wins over the St. Louis Cardinals (42-36) after a 9-4 win on Wednesday.
St. Louis has lost five of the last seven games as the hitting hasn’t been able to keep up with the pitching staff. The Cardinals rank 28th in ERA (5.87) over the past 15 days, while the offense is sixth in batting average (.273) with the eighth-most runs scored (65) in 13 games (5-8 record). The Cardinals have surrendered at least four runs in 10 of the last 13 games.
In June, Arizona has one of the worst offenses with a .224 batting average (26th), the fifth-fewest home runs (22), and ranked 22nd in runs scored (82). The Diamondbacks pitchers are posting a 4.99 ERA (26th) and it’s worsened over the last six games (5.77 ERA). Zac Gallen will take the mound and he’s coming off a season-worst nine earned runs allowed, while sporting a 8.85 ERA in June.
Let’s dive into the matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Diamondbacks at Cardinals
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Date: Thursday, June 25, 2026
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Odds for the Diamondbacks at the Cardinals
The latest odds as of Thursday:
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Moneyline: St. Louis Cardinals (-136), Arizona Diamondbacks (+113)
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Spread: Cardinals -1.5 (+152), Nationals +1.5 (-185)
Probable starting pitchers for Diamondbacks at Cardinals
2026 stats: 79.2 IP, 3-6, 6.10 ERA, 1.63 WHIP, 52 K, 25 BB
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Cardinals: Michael McGreevy
2026 Stats: 83.1 IP, 3-6, 3.35 ERA, 1.15 WHIP, 53 Ks, 20 BB
Who’s Hot? Who’s Not
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The Cardinals’ Jordan Walker is hitting .290 with 88 hits, 18 home runs and 58 RBI over 303 at-bats
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The Cardinals’ Pedro Pages is hitting .217 with 28 hits and 35 strikeouts over 129 at-bats
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The Diamondbacks’ Corbin Carroll is hitting .279 with 80 hits, 13 home runs, and 42 RBI over 287 at-bats
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The Diamondbacks’ Nolan Arenado is hitting .238 with 61 hits and 58 strikeouts over 256 at-bats
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Top betting trends & insights to know ahead of Diamondbacks at Cardinals
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St. Louis is 46-32 ATS, ranking second-best
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Arizona is 45-35 ATS, ranking sixth-best
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St. Louis is 39-34-5 to the Under, ranking ninth-best
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Arizona is 42-34-4 to the Under, ranking second-best
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St. Louis is 24-17 ATS, ranking fourth-best
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Arizona is 22-17 ATS, ranking seventh-best
Expert picks & predictions for tonight’s game between the Diamondbacks and the Cardinals
Rotoworld Bet Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Thursday’s game between the Diamondbacks and the Cardinals:
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Moneyline: NBC Sports Bet is recommending a play on the Cardinals on the Moneyline.
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Spread: NBC Sports Bet is leaning towards a play ATS on the Cardinals at -1.5.
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Total: NBC Sports Bet is recommending a play on the Under on the Game Total of 9.0
Follow our experts on socials to keep up with all the latest content from the staff:
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Jay Croucher (@croucherJD)
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Drew Dinsick (@whale_capper)
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Vaughn Dalzell (@VmoneySports)
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Trysta Krick (@Trysta_Krick)
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