It’s Tuesday, August 26 and the Pirates (57-74) are in St. Louis to take on the Cardinals (64-67). Mitch Keller is slated to take the mound for Pittsburgh against Andre Pallante for St. Louis.
The Cardinals rallied over the Pirates with a walk-off homer via Alec Burleson to tie up the season series at five wins apiece. The loss ended the Pirates’ four-game winning streak and snapped the Cardinals two-game losing streak.
Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Pirates at Cardinals
- Date: Tuesday, August 26, 2025
- Time: 7:45PM EST
- Site: Busch Stadium
- City: St. Louis, MO
- Network/Streaming: SNP, FDSNMW
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Pirates at the Cardinals
The latest odds as of Tuesday:
- Moneyline: Pirates (+109), Cardinals (-130)
- Spread: Cardinals -1.5
- Total: 8.0 runs
Probable starting pitchers for Pirates at Cardinals
- Pitching matchup for August 26, 2025: Mitch Keller vs. Andre Pallante
- Pirates: Mitch Keller, (5-12, 4.35 ERA)
Last outing: 13.50 ERA, 5 Earned Runs Allowed, 7 Hits Allowed, 3 Walks, and 4 Strikeouts - Cardinals: Andre Pallante, (6-11, 5.17 ERA)
Last outing: 8.44 ERA, 5 Earned Runs Allowed, 8 Hits Allowed, 3 Walks, and 4 Strikeouts
- Pirates: Mitch Keller, (5-12, 4.35 ERA)
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Top betting trends & insights to know ahead of Pirates at Cardinals
- St. Louis is 5-5 versus Pittsburgh this season
- Pittsburgh is 4-1 in the last 5 games
- The Pirates have a losing record this season (57-74) but they have won 5 of their last 6 games
- Each of the last 5 matchups between the Cardinals and the Pirates have stayed under the Total
- The Pirates have failed to cover the Run Line in 3 straight road games against the Cardinals
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s game between the Pirates and the Cardinals
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Tuesday’s game between the Pirates and the Cardinals:
- Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Pittsburgh Pirates at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
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- Trysta Krick (@Trysta_Krick)
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